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Treatment and resistance in a CML model
Last modified: 2023-05-15
Abstract
Our paper focuses on a delay-differential equations model which describes the evolution of leukemic andhealthy cells in chronic myeloid leukemia (CML). The system includes the action of the immune systemand the influence of treatment with Imatinib. We model the situation in which the cells develop resistanceto treatment by a Goldie-Coldman law.